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Published on Oct 30, 2024

Targeting erbB Pathways in Breast Cancer: Dual Kinase Inhibition for Brain Metastasis and Prevention of p185HER2/Neu ...

Introduction Human epidermal growth factor receptors (HERs) are part of the epidermal growth factor receptor (EGFR) family and consist of four subtypes: HER1 (EGFR, erbB1), HER2 (erbB2, HER2/neu), HER3 (erbB3), and HER4 (erbB4).1–5 The erbB2 gene …

Source: Dove Medical Press - Neutral
Published on Nov 2, 2024

Vir Biotechnology, Inc. (NASDAQ:VIR) Q3 2024 Earnings Call Transcript

Vir Biotechnology, Inc. (NASDAQ:VIR) Q3 2024 Earnings Call Transcript October 31, 2024 Vir Biotechnology, Inc. misses on earnings expectations. Reported EPS is $-1.56 EPS, expectations were $-0.96. Operator: [Call starts abruptly] …Vir’s Third Quarter 2024 …

Source: Insider Monkey - Neutral
Published on Oct 31, 2024

Kelun-Biotech's TROP2-ADC SKB264 (Sac-TMT) Third NDA Accepted By NMPA, Locally Advanced Or Metastatic EGFR-Mutant NSCLC

(MENAFN- PR Newswire) CHENGDU, China, Oct. 31, 2024 /PRNewswire/ -- The new drug application (NDA) (the " Application ") based on the positive results from the pivotal phase III OptiTROP-Lung04 study of sacituzumab tirumotecan (sac-TMT, …

Source: MENAFN - Uncategorized
Published on Nov 2, 2024

Study links methylmalonic acid to weakening of immune cells in lung cancer

A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may promote lung cancer progression. Moffitt Cancer Center researchers have found …

Source: ScienceDaily - Label Pending
Published on Nov 2, 2024

Research Sheds Light on Gaps in Care Faced by Patients With MBD From Primary Cancers

Patients with secondary metastatic involvement in the musculoskeletal system due to primary cancers face high risks of health-related challenges, especially due to metastases or metastatic bone disease (MBD), which can severely impair quality of life, …

Source: OncLive - Label Pending
Published on Nov 2, 2024

Photo-Thermally Controllable Tumor Metabolic Modulation to Assist T Cell Activation for Boosting Immunotherapy

Introduction Cancer immunotherapy marks a transformative progress in oncology, principally focusing on activating or rejuvenating the patient’s immune system to detect and eradicate tumor cells.1–3 However, various immunosuppressive mechanisms within the …

Source: Dove Medical Press - Neutral
Published on Nov 2, 2024

Comprehensive Pan-Cancer Analysis of the Prognostic Role of KLF Transcription Factor 2 (KLF2) in Human Tumors

Introduction The incidence and mortality of malignant tumors are on the rise, which has become the second leading cause of death in the world.1 With the in-depth understanding of the underlying mechanisms of tumorigenesis, the treatment options for …

Source: Dove Medical Press - Neutral
Published on Nov 1, 2024

Use of New Cancer Drugs Needs a ‘Tincture of Time and Information’

While effective new cancer therapies have been approved in recent years, clinician education and patient advocacy is key to putting these drugs into practice, explained Jamie L. Carroll, APRN, CNP, MSN, of the Mayo Clinic. In a recent Community Case Forum, …

Source: Oncology Nursing News - Label Pending
Published on Nov 1, 2024

Oncology Drugs Approved by the FDA in October 2024

In October, several cancer therapies received approval from the Food and Drug Administration in diseases including non-small cell lung cancer, breast cancer, gastric and GEJ adenocarcinoma, acute lymphoblastic leukemia and chronic myeloid leukemia. Here is …

Source: Cure Today - Neutral
Published on Nov 2, 2024

High RRM2 Correlates with Mitochondrial and Immune Responses in the Eosinophilic Subtype of Clear Cell Renal Cell ...

Introduction Renal cell carcinoma (RCC) is one of the ten most often diagnosed malignancies worldwide.1,2 Clear cell renal cell carcinoma (ccRCC) is the most prevalent histological subtype of RCC, accounting for approximately 75% of all RCC cases.3,4 …

Source: Dove Medical Press - Neutral
Published on Nov 1, 2024

Charlene Alloway (1955 – 2024)

(Resident Of Bryan) Charlene J. Alloway, 69, of Bryan, Ohio, passed away at The Laurels of Defiance on Tuesday, October 29, 2024, after a four-year battle with metastatic breast cancer stage IV. Charlene was born on September 11, 1955, in Bryan, daughter …

Source: The Village Reporter - Ohio - Neutral
Published on Nov 1, 2024

Quality of life on Verzenio

Verzenio is an oral tablet that you take twice daily. The drug works to slow the growth of HR+/HER2- breast cancer by blocking certain proteins that allow these cancer cells to grow. Blocking this activity prevents these cells from multiplying (making …

Source: Medical News Today - Neutral
Published on Nov 2, 2024

Combination of Methotrexate and Resveratrol Reduces Pro-Inflammatory Chemokines in Human THP-1 Cells

Introduction Methotrexate (MTX), an anti-inflammatory and anti-metabolic drug,1 is widely used as a therapeutic agent in a number of inflammatory diseases such as inflammatory bowel disease,2 psoriasis,3 rheumatoid arthritis,1 systemic lupus erythematosus, …

Source: Dove Medical Press - Neutral
Published on Nov 1, 2024

FDA's October 2024 Highlights: Advancing Treatments in Oncology

October 2024 brought a number of significant FDA actions across oncology, focusing on new approvals, priority reviews, and designations aimed at broadening therapeutic options and improving diagnostics across cancer types. Some highlights include the FDA’s …

Source: Targeted Oncology - Label Pending
Published on Oct 31, 2024

The Relentless Optimism of Beatriz da Costa

You can keep reading for free! At Hyperallergic, we strive to make art more inclusive, so you’ll never hit a paywall when reading our articles. But, as an independent publication, we rely on readers like you to keep our high-quality coverage free and …

Source: Hyperallergic - Left-wing
Published on Nov 1, 2024

What are estrogen-dependent cancers?

Estrogen-dependent cancers are cancers that grow in response to the hormone estrogen. These include certain types of breast cancer, uterine cancer, and ovarian cancer. In these cancers, estrogen can bind to receptors on cancer cells, fueling their growth …

Source: Medical News Today - Neutral
Published on Oct 31, 2024

A Month Without Pink, Almost

October went by in a blink of the eye, no pink. Well, almost no pink. I did pause at Kroger one afternoon to covet a dozen small pink roses, only 10 dollars, and imagined arranging them into two vases, one for me and one for a friend who is a breast cancer …

Source: Cure Today - Neutral
Published on Oct 31, 2024

NCODA Fall Summit Recap: Key Sessions and Expert Interviews From the 2024 Meeting

Pharmacy Times® covered the 2024 NCODA International Fall Summit in Orlando, Florida, from October 23 to October 25. The meeting was full of clinical science breakthroughs and inspiring stories from patients. The summit opened with a powerful keynote …

Source: Pharmacy Times - Neutral
Published on Nov 1, 2024

3D tumor mapping reveals new insights into cancer biology and treatment

A new analysis led by researchers at Washington University School of Medicine in St. Louis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -; and the cells of a tumor…

Source: Medical News - Neutral

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Published on November 2, 2024 - 13:00 GMT

Sermonix Surveys Find Vaginal/Sexual Health Symptoms Are Among Most Significant Issues Affecting Lives of ER+/HER2- ...

COLUMBUS, Ohio, Nov. 02, 2024 (GLOBE NEWSWIRE) -- Sermonix Pharmaceuticals Inc., a privately held biopharmaceutical company developing innovative therapeutics to specifically treat metastatic breast cancers (mBC), today broadly shared conclusions from a …

Distribution channels: Science ...
Published on November 2, 2024 - 13:00 GMT

Sermonix Pharmaceuticals’ Lasofoxifene Is Well Tolerated, Demonstrates Promising Ki67 Suppression in Phase 2 I-SPY 2 Arm ...

COLUMBUS, Ohio, and SAN FRANCISCO, Nov. 02, 2024 (GLOBE NEWSWIRE) -- Sermonix Pharmaceuticals Inc., a privately held biopharmaceutical company developing innovative therapeutics to specifically treat metastatic breast cancers (mBC), and Quantum Leap …

Distribution channels: Healthcare & Pharmaceuticals Industry

Published on November 1, 2024 - 21:30 GMT

ALX Oncology Announces Results from Phase 1b/2 Trial of Evorpacept in Combination with Zanidatamab will be Presented at ...

SOUTH SAN FRANCISCO, Calif., Nov. 01, 2024 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., (“ALX Oncology” or “the Company”) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing therapies that boost the immune system to treat cancer in new ways …

Distribution channels: Culture, Society & Lifestyle, Healthcare & Pharmaceuticals Industry ...
Published on November 1, 2024 - 21:30 GMT

OnKure to Present Clinical and Preclinical Data for OKI-219 at the 2024 San Antonio Breast Cancer Symposium

OnKure to host a conference call to review key data presented at SABCS and provide a general corporate update on Friday, December 13, 2024 at 8:00 a.m. ET BOULDER, Colo., Nov. 01, 2024 (GLOBE NEWSWIRE) -- OnKure Therapeutics, Inc. (NASDAQ: OKUR), a …

Distribution channels: Healthcare & Pharmaceuticals Industry, Media, Advertising & PR ...

Published on November 1, 2024 - 12:00 GMT

The MUHC Foundation and the Beat 92.5’s Raise Craze raises $95,000 to help strike out breast cancer

MONTREAL, Nov. 01, 2024 (GLOBE NEWSWIRE) -- The MUHC Foundation, in collaboration with The Beat 92.5 and Pink in the City, raised $95,000 at the 9th edition of the MUHC Foundation’s Raise Craze to support breast cancer care at the McGill University Health …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on October 31, 2024 - 15:13 GMT

Expanding access to faster, cheaper radiation treatment for U.S. breast cancer patients

Hypofractionated whole-breast irradiation (HF-WBI) is a method of delivering radiation therapy after breast-conserving surgery. The treatment is highly efficient, less expensive, and takes less time; however, it is not currently the standard method of …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on October 31, 2024 - 12:15 GMT

Atossa Therapeutics Releases Promising Preliminary Analysis Demonstrating (Z)-Endoxifen’s Potential to Rapidly Reduce Ki-...

(Z)-endoxifen at 10 mg once daily met the primary endpoint with 19/20 (95%) receiving > 75 % of planned treatment in I-SPY-2 Phase 2 Trial Low dose (Z)-endoxifen was well tolerated and demonstrated promising rapid activity in reducing 3-wk Ki-67 and …

Distribution channels: Healthcare & Pharmaceuticals Industry, Media, Advertising & PR ...
Published on October 31, 2024 - 01:15 GMT

Researchers map communities of single cells in metastatic breast cancers

A single biopsy from a metastatic breast cancer tumor contains hundreds of thousands of cells – some cancerous and others part of the complex web of immune cells, blood vessels, and supportive tissue that surround a tumor. Researchers have typically …

Distribution channels: Healthcare & Pharmaceuticals Industry

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Published on November 2, 2024 - 13:00 GMT

Galan Aesthetics Wins Prestigious 2024 Best of Florida Regional Award

MIAMI, FL, UNITED STATES, November 2, 2024 /⁨EINPresswire.com⁩/ -- Galan Aesthetics, a leading provider of non-surgical aesthetic treatments in Miami, has been honored with the 2024 Best of Florida Regional Award, a testament to the clinic’s …

Distribution channels: Beauty & Hair Care, Business & Economy ...
Published on November 2, 2024 - 18:46 GMT

Survey: Nearly Half of Americans Expect Their Mental Health to be Negatively Affected By the Presidential Election ...

NEW YORK CITY, Nov. 02, 2024 (GLOBE NEWSWIRE) -- An annual holiday stress survey has also revealed the stakes of the upcoming presidential election in mental health terms: nearly half of the country will feel negative mental health effects if their …

Distribution channels: Healthcare & Pharmaceuticals Industry, Media, Advertising & PR ...
Published on November 2, 2024 - 13:00 GMT

Sermonix Pharmaceuticals’ Lasofoxifene Is Well Tolerated, Demonstrates Promising Ki67 Suppression in Phase 2 I-SPY 2 Arm ...

COLUMBUS, Ohio, and SAN FRANCISCO, Nov. 02, 2024 (GLOBE NEWSWIRE) -- Sermonix Pharmaceuticals Inc., a privately held biopharmaceutical company developing innovative therapeutics to specifically treat metastatic breast cancers (mBC), and Quantum Leap …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on November 2, 2024 - 12:32 GMT

Optimal Breathing Holds its Annual Black Friday Sale

FORT MILL, S.C., Nov. 02, 2024 (GLOBE NEWSWIRE) -- Optimal Breathing will hold its annual Black Friday Sale online at www.optimalbreathing.com, starting November 1, 2024. This sale will offer customers a flat 15% OFF on all orders above $250, making it …

Distribution channels: Healthcare & Pharmaceuticals Industry, Media, Advertising & PR ...
Published on November 1, 2024 - 22:37 GMT

Gluckstein Lawyers Ranked by Best Law Firms™- Canada in 2025

TORONTO, ONTARIO, CANADA, November 1, 2024 /⁨EINPresswire.com⁩/ -- Gluckstein Lawyers is proud to announce its recognition in the 2025 edition of Best Law Firms™ - Canada, highlighting the firm’s unwavering commitment to legal excellence. Ranked as …

Distribution channels: Culture, Society & Lifestyle, Healthcare & Pharmaceuticals Industry ...
Published on November 2, 2024 - 10:18 GMT

Merus gibt Finanzergebnisse für das dritte Quartal 2024 bekannt und informiert über den aktuellen Geschäftsverlauf

Phase-III-Zulassungsstudien zur Bewertung von Petosemtamab in Kombination mit Pembrolizumab in der Erstlinie und Petosemtamab-Monotherapie gegen rezidivierenden/metastasierendes Plattenepithelkarzinom des Kopf- und Halsbereichs in der Zweit- und …

Distribution channels: Business & Economy, Healthcare & Pharmaceuticals Industry ...
Published on November 2, 2024 - 10:18 GMT

Merus annonce ses résultats financiers pour le troisième trimestre 2024 et fait le point sur ses activités

L’inclusion est en cours pour les essais d’enregistrement de phase III, pour l’évaluation du pétosemtamab en association avec le pembrolizumab en traitement de 1re intention, et pour l’évaluation du pétosemtamab en traitement monothérapique de 2e et 3e …

Distribution channels: Business & Economy, Healthcare & Pharmaceuticals Industry ...
Published on November 1, 2024 - 21:00 GMT

Sustainable Chic: Mima USA Unveils the White Creo Stroller, Offering a Clean Slate in Baby Gear Design

Mima USA unveils the newborn-ready white Creo stroller for Spring 2025, blending chic minimalism with eco-smart design. EL MONTE, CA, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- Mima USA, a leader in innovative, high-quality baby gear, …

Distribution channels: Consumer Goods, Culture, Society & Lifestyle ...
Published on November 1, 2024 - 20:25 GMT

USA Fibroid Centers Goes Live Behind the Scenes with Reality TV Star Toya Johnson

Reality star Toya Johnson joins USA Fibroid Centers to raise awareness about fibroids. Tune in to IG Live Nov. 4th at 8 PM EST for a discussion with Kym Lee ATLANTA, GA, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- USA Fibroid Centers …

Distribution channels: Business & Economy, Culture, Society & Lifestyle ...
Published on November 1, 2024 - 19:27 GMT

Magnetic Products Inc. (MPI) Launches the Patented Wave Magnet™

Innovative Design, Self-Cleaning, Sensor-Enabled Intell-I-Mag® Smart Monitoring Magnetic Separator for Pneumatic Conveying HIGHLAND, MI, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- MPIMAGNET.COM—Magnetic Products Inc. (MPI) will …

Distribution channels: Automotive Industry, Chemical Industry ...
Published on November 1, 2024 - 19:27 GMT

Magnetic Products Inc. (MPI) Launches the Patent-Pending Blade Magnet™

Intell-I-Mag® Liquid Trap Separator: The most powerful liquid trap the industry has ever seen HIGHLAND, MI, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- MPIMAGNET.COM—Magnetic Products Inc. (MPI) will introduce the Blade Magnet™ (patent …

Distribution channels: Chemical Industry, Food & Beverage Industry ...
Published on November 1, 2024 - 18:57 GMT

Immigration Canada New Regulations : Shifts in Targets, Changes in Temporary Residency, and Work Permit Restrictions

Canada sets new immigration targets, caps international students, and refines work permits to balance growth and social needs. MONTREAL, QC, CANADA, November 1, 2024 /⁨EINPresswire.com⁩/ -- October 2024 - The Immigration, Refugees and Citizenship …

Distribution channels: Business & Economy, Education ...
Published on November 1, 2024 - 18:01 GMT

Integrative Techniques in Counseling: Combining Methods for Better Outcomes

NEW ORLEANS, LA, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- Dr. Arwen Podesta, owner of Podesta Wellness in New Orleans, sheds light on the benefits of integrative counseling, a method that incorporates multiple therapeutic approaches …

Distribution channels: Culture, Society & Lifestyle, Healthcare & Pharmaceuticals Industry ...
Published on November 1, 2024 - 17:46 GMT

Easterseals Northern California Celebrates New San Jose Clinic Providing Autism and I/DD Services

Easterseals Northern California cuts the ribbon on its newest clinic, providing services to San Jose and Santa Clara County. SAN JOSE, CA, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- Easterseals Northern California officially opened …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on November 1, 2024 - 17:33 GMT

South Beach Wellness Center Expands to Lutz/Wesley Chapel, Providing Premier Health Solutions for Perimenopausal Women

South Beach Wellness Center Expands to Lutz/Wesley Chapel, Offering Comprehensive Solutions for Perimenopausal Health and Women's Wellness LUTZ, FL, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- Many women experience unwanted …

Distribution channels: Beauty & Hair Care, Consumer Goods ...
Published on November 1, 2024 - 17:21 GMT

After Lecturing Across Programs at U of Iowa, TravelingWiki CEO Presents at 2024 Autism Society of Iowa Fall Conference

After Lecturing Across Programs at the University of Iowa, TravelingWiki Foundation CEO Presents at 2024 Autism Society of Iowa Fall Conference DES MOINES, IA, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- As part of extensive work to …

Distribution channels: Aviation & Aerospace Industry, Healthcare & Pharmaceuticals Industry ...
Published on November 1, 2024 - 16:50 GMT

Texas Laparoscopic Consultants Introduces Revolutionary Spatz Balloon Procedure

HOUSTON, TX, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- Texas Laparoscopic Consultants is excited to announce the launch of the Spatz3 Intragastric Balloon, an innovative, FDA-approved adjustable balloon designed to help patients …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on November 1, 2024 - 16:34 GMT

Dr. Amit Taggar, MD, Joins AWC Advanced Wound Care, Expanding Expertise in Patient-Centered Care

Innovative Mobile Wound Care Solutions Now Supported by Leading Surgical Expert TAMPA, FL, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- AWC Advanced Wound Care proudly announces the addition of Dr. Amit Taggar, MD, a distinguished …

Distribution channels: Companies, Culture, Society & Lifestyle ...
Published on November 1, 2024 - 16:00 GMT

DiabetesSisters Celebrates National Diabetes Month with Programs Highlighting Innovation, Empowerment, & Women’s Health

Empowering Women with Diabetes: DiabetesSisters Unveils Free Educational Webinars, Peer Support, and Expert Talks for National Diabetes Month. RALEIGH, NC, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- DiabetesSisters, a national …

Distribution channels: Culture, Society & Lifestyle, Healthcare & Pharmaceuticals Industry ...
Published on November 1, 2024 - 15:51 GMT

Reconnect Relationship Wins Global Award for Campaign Breaking Stereotypes & Empowering Judgment-Free Mental Health Care

Start-Up Achievement of Year Awarded to Reconnect Relationship: Only Mental Health Company to Win Award in 2024 Globees International Business Award Competition BOCA RATON, FL, UNITED STATES, November 1, 2024 /⁨EINPresswire.com⁩/ -- Reconnect …

Distribution channels: Business & Economy, Consumer Goods ...